Cheesy Meatloaf Casserole is a comforting dish that brings together the classic flavors of meatloaf in a convenient casserole format. It’s hearty, cheesy, and perfect for busy weeknights. With simple ingredients and a few easy steps, you’ll have a delicious meal the whole family will love!
Why You’ll Love This Cheesy Meatloaf Casserole
- Packed with flavor from the juicy ground beef and melted cheese.
- Quick to prepare, making it ideal for busy families.
- Great for meal prep; leftovers make for tasty lunches.
- Kid-friendly and sure to please even the pickiest eaters.
- One-dish meal that minimizes cleanup.
Ingredients Needed
-
Protein
- 1 lb ground beef
-
Rice/Grains
- 1 cup breadcrumbs
-
Veggies
- 1 onion, chopped
-
Cheese
- 1 cup shredded cheese
-
Liquid
- 1/2 cup milk
-
Binders
- 1 egg
-
Sauce
- 1/2 cup ketchup
-
Spices
- 1 tsp garlic powder
- Salt and pepper to taste
Step-by-Step Instructions
Step 1:
Preheat the oven to 350°F (175°C).
Step 2:
In a large bowl, combine ground beef, breadcrumbs, 1/2 cup of shredded cheese, milk, egg, chopped onion, garlic powder, salt, and pepper.
Step 3:
Mix the ingredients until well combined.
Step 4:
Spread the meat mixture evenly into a greased casserole dish.
Step 5:
Top with the remaining shredded cheese and drizzle ketchup over the top.
Step 6:
Bake for 45-50 minutes or until fully cooked through.
Step 7:
Let it cool for a few minutes before serving.
Serving Suggestions Cheesy Meatloaf Casserole
- Serve with a side of steamed vegetables for a balanced meal.
- Pair with mashed potatoes or a fresh garden salad.
- Add some pickles or coleslaw on the side for crunch.
- Enjoy with a glass of iced tea or lemonade.
Tips for Success Cheesy Meatloaf Casserole
- Ensure the meatloaf is well-mixed for even cooking.
- Use lean ground beef for a lighter version if desired.
- Store leftovers in the fridge for up to three days.
- Reheat in the oven or microwave for best results.
Variations
Here are a few easy ways to change it up:
- Substitute ground turkey or chicken for a leaner option.
- Add chopped bell peppers or mushrooms for extra veggies.
- Spice it up with diced jalapeños or chili powder for heat.
- Use dairy-free cheese and milk for a dairy-free option.
Follow us on Pinterest for more cozy ideas.
Can I make Cheesy Meatloaf Casserole ahead of time?
What can I substitute for ground beef?
How should I store leftovers?
Can I add vegetables to the casserole?

Cheesy Meatloaf Casserole
Ingredients
Method
- Preheat the oven to 350°F (175°C).
- In a large bowl, combine ground beef, breadcrumbs, 1/2 cup of shredded cheese, milk, egg, chopped onion, garlic powder, salt, and pepper.
- Mix the ingredients until well combined.
- Spread the meat mixture evenly into a greased casserole dish.
- Top with the remaining shredded cheese and drizzle ketchup over the top.
- Bake for 45-50 minutes or until fully cooked through.
- Let it cool for a few minutes before serving.